The Evergrande Center for Immunologic Diseases aims to transform the understanding and treatment of chronic inflammation through our use of cutting edge technologies and collaborative, multidisciplinary research.
http://evergrande.hms.harvard.edu/
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Evergrande Center for Immunologic Diseases | evergrande.hms.harvard.edu Reviews
https://evergrande.hms.harvard.edu
The Evergrande Center for Immunologic Diseases aims to transform the understanding and treatment of chronic inflammation through our use of cutting edge technologies and collaborative, multidisciplinary research.
evergrande.hms.harvard.edu
Metabolic Diseases | Evergrande Center for Immunologic Diseases
http://evergrande.hms.harvard.edu/metabolic-diseases
Skip to main content. Transgenic and KO Core. The prevalence of obesity and diabetes is increasing world-wide, and although increasing energy consumption and reduced physical exercise play key roles, data suggest that chronic low-grade inflammation is the underlying cause. Studies in both mice and humans provide evidence that over-feeding and excess consumption of nutrients evoke an inflammatory response in adipose tissue, muscle, and liver. 77 Avenue Louis Pasteur.
Scholar Exchange Program | Evergrande Center for Immunologic Diseases
http://evergrande.hms.harvard.edu/scholar-exchange-program
Skip to main content. Transgenic and KO Core. Our inaugural Evergrande Scholar, Zimeng Zhang a graduate of Zhejiang University, matriculated into the Harvard Immunology Graduate Program in Fall 2014. Transgenic and KO Core. 77 Avenue Louis Pasteur. Admin@evergrande.hms.harvard.edu.
Core Faculty | Evergrande Center for Immunologic Diseases
http://evergrande.hms.harvard.edu/core-faculty
Skip to main content. Transgenic and KO Core. Vijay K. Kuchroo, DVM, PhD. Director, Evergrande Center for Immunologic Diseases. Samuel L. Wasserstrom Professor of Neurology, Harvard Medical School. DUBA-UBR5 axis: other than transactivation. Wu C, Chen Z, Kuchroo VK. Cell Res. 2015 Mar;25(3):273-4. doi: 10.1038/cr.2015.13. Epub 2015 Jan 30. PMID: 25633593; PMC4349248. A T cell extrinsic mechanism by which IL-2 dampens Th17 differentiation. Ezh2 lines up the chromatin in T regulatory cells. Coinhibitory r...
Autoimmune Diseases | Evergrande Center for Immunologic Diseases
http://evergrande.hms.harvard.edu/autoimmune-diseases
Skip to main content. Transgenic and KO Core. In autoimmune diseases such as Multiple Sclerosis, Type 1 Diabetes, and Rheumatoid Arthritis, self-reactive T and B cells escape regulatory checkpoints in lymphoid tissues where they develop and expand. This leads to the generation of antibodies and cytotoxic cells, which destroy brain, pancreatic, and joint tissues, respectively. The Center is focused on basic research work, identifying cells and molecules involved in chronic inflammation.
Evergrande Center for Immunologic Diseases
http://evergrande.hms.harvard.edu/home
Skip to main content. Transgenic and KO Core. The 2016 Symposium will be held on July 15th at Harvard Medical School. Registration required. Cutting edge approaches to determine mechanisms of inflammation. Inspiring the best young minds to pursue academic and professional careers focused on immunology. The 2016 Symposium will be held on Friday, July 15th at the Joseph B. Martin Conference Center at Harvard Medical School. Registration required. Lawrence Steinman, MD. What is the Evergrande Center? The Ev...
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Sharpe Laboratory
http://sharpelab.hms.harvard.edu/home
Skip to main content. Coinhibitory Pathways in Immunotherapy for Cancer. Baumeister SH, Freeman GJ, Dranoff G, Sharpe AH. Coinhibitory Pathways in Immunotherapy for Cancer. Annu Rev Immunol. 2016;34 :539-73. T follicular regulatory cells. Sage PT, Sharpe AH. T follicular regulatory cells. Immunol Rev. 2016;271 (1) :246-59. Distinct clinical patterns and immune infiltrates are observed at time of progression on targeted therapy versus immune checkpoint blockade for melanoma. May 17, 2016. May 1, 2016.
Join Us | Sharpe Laboratory
http://sharpelab.hms.harvard.edu/join-us
Skip to main content. Sharpe lab is always happy to hear from highly motivated individuals interested in T cell costimulation and immunoregulation. We are dedicated to fostering a collaborative environment and welcome individuals with similar attitudes to join our lab. The successful applicant will have ample opportunities to develop new skills, and will work in a world-class scientific environment with full access to cutting edge tools and technologies. To apply, please send. Students interested in purs...
T follicular regulatory cells. | Sharpe Laboratory
http://sharpelab.hms.harvard.edu/publications/t-follicular-regulatory-cells
Skip to main content. T follicular regulatory cells. Sage PT, Sharpe AH. T follicular regulatory cells. Immunol Rev. 2016;271 (1) :246-59. Department of Microbiology and Immunobiology. 77 Avenue Louis Pasteur, NRB 837. Boston, MA 02115.
Resources | Sharpe Laboratory
http://sharpelab.hms.harvard.edu/resources
Skip to main content. Request Mice from Sharpe Lab. To request research mice from Sharpe lab please send an email to sharpe lab@hms.harvard.edu. With the following information:. Name and contact information for the principal investigator. Description of proposed research to initiate a Material Transfer Agreement (MTA). Recipients are responsible for all shipping costs plus a $200 packing and materials fee. A number of our strains are available from the Jackson Labs and the MMRRC:. Provides DNA sequencing...
Lab Fun | Sharpe Laboratory
http://sharpelab.hms.harvard.edu/lab-fun
Skip to main content. Sea Crest Beach Hotel, Falmouth, MA. Sea Crest Beach Hotel, Falmouth, MA. Sharpies at the beach. Sea Crest Beach Hotel, Falmouth, MA. 2012 Immunology Program Retreat. Sharpe lab graduate students. Visit to Gillette Stadium. Larz Anderson Park, Brookline, MA. 2016 Escape the Room Boston. Sharpe Haining Holiday Gift Drive. Dr Sharpe and her minions. 2015 St. Patrick's Day. We caught a leprechaun! Beware of sharp objects . . . Let the carving begin! Anything Goes Friday, Sharpie style!
Congratulations, Peter! | Sharpe Laboratory
http://sharpelab.hms.harvard.edu/news/congratulations-peter-1
Skip to main content. May 1, 2016. Congratulations Peter for the publication of your review "T follicular regulatory cells" in. Department of Microbiology and Immunobiology. 77 Avenue Louis Pasteur, NRB 837. Boston, MA 02115.
Congratulations, Frank! | Sharpe Laboratory
http://sharpelab.hms.harvard.edu/news/congratulations-frank
Skip to main content. May 17, 2016. Congratulations Frank for the publication of your review "Coinhibitory Pathways in the B7-CD28 Ligand-Receptor Family" in. Department of Microbiology and Immunobiology. 77 Avenue Louis Pasteur, NRB 837. Boston, MA 02115.
Coinhibitory Pathways in Immunotherapy for Cancer. | Sharpe Laboratory
http://sharpelab.hms.harvard.edu/publications/coinhibitory-pathways-immunotherapy-cancer
Skip to main content. Coinhibitory Pathways in Immunotherapy for Cancer. Baumeister SH, Freeman GJ, Dranoff G, Sharpe AH. Coinhibitory Pathways in Immunotherapy for Cancer. Annu Rev Immunol. 2016;34 :539-73. Department of Microbiology and Immunobiology. 77 Avenue Louis Pasteur, NRB 837. Boston, MA 02115.
People | Sharpe Laboratory
http://sharpelab.hms.harvard.edu/people
Skip to main content. George Fabyan Professor of Comparative Pathology. Interim Co-Chair, Microbiology and Immunobiology. Co-Director, Evergrande Center for Immunologic Diseases. Arlene Sharpe is the George Fabyan Professor of Comparative Pathology, Head of the Division of Immunology, and Interim Co-Chair of the Department of Read more about Arlene Sharpe. 77 Avenue Louis Pasteur, NRB 837. Boston, MA 02115. Arlene sharpe at hms.harvard.edu. Fdbrown at fas.harvard.edu. Baolinchang at yahoo.com. Originally...
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Evergrande Center for Immunologic Diseases
Skip to main content. Transgenic and KO Core. Cutting edge approaches to determine mechanisms of inflammation. Jeffrey Flier, Dean of Harvard Medical School, at the launch of the Evergrande Center for Immunologic Disease. March 2014. Inspiring the best young minds to pursue academic and professional careers focused on immunology. The Evergrande Center convenes faculty and students from across Harvard and its affiliates. What is the Evergrande Center? Tuesday, January 6, 2015. Wednesday, November 26, 2014.
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