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LIFE - LINCS Information FramEwork

Browse by Small molecules(9072). Browse by Kinase proteins(475). The LIFE search engine integrates all LINCS content leveraging a semantic knowledge model and common LINCS metadata standards. LIFE makes LINCS content discoverable and includes aggregate results linked to the Harvard Medical School. And other LINCS centers, who provide more information including experimental conditions and raw data.

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LIFE - LINCS Information FramEwork | life.ccs.miami.edu Reviews
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Browse by Small molecules(9072). Browse by Kinase proteins(475). The LIFE search engine integrates all LINCS content leveraging a semantic knowledge model and common LINCS metadata standards. LIFE makes LINCS content discoverable and includes aggregate results linked to the Harvard Medical School. And other LINCS centers, who provide more information including experimental conditions and raw data.
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2 browse
3 structure
4 statistics
5 browse by bioassays 10
6 bioassays
7 and broad institute
8 team
9 terms of use
10 acknowledgements
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LIFE - LINCS Information FramEwork | life.ccs.miami.edu Reviews

https://life.ccs.miami.edu

Browse by Small molecules(9072). Browse by Kinase proteins(475). The LIFE search engine integrates all LINCS content leveraging a semantic knowledge model and common LINCS metadata standards. LIFE makes LINCS content discoverable and includes aggregate results linked to the Harvard Medical School. And other LINCS centers, who provide more information including experimental conditions and raw data.

INTERNAL PAGES

life.ccs.miami.edu life.ccs.miami.edu
1

Acknowledgement

http://life.ccs.miami.edu/life/acknowledgement

The University of Miami LINCS Center. Is a member of the LINCS Consortium. Supported by the NIH Common Fund. We gratefully acknowledge the following contributions:. The LINCS Data Production Centers (U54) and Technology Centers (U01) for taking the time to work with us and provide the data and metadata. Harvard Medical School (HMS) LINCS Center (U54). LINCS assays indexed in LIFEwrx: Apoptosis assay. Cell cycle state assay. Cell growth inhibition assay. Broad Institute LINCS Center (U54). Dr Shamu and te...

2

Statistics Page

http://life.ccs.miami.edu/life/statistics

Welcome to the new Summary Page. This page displays summary statistics regarding the data indexed by LIFEwrx. Statistics are currently calculated only for those assays for which normalized perturbation data is available (9 out of 13 assays searchable in LIFEwrx). Help is available by clicking on the help icon next to Bioassays. All feedback is welcome and can be provided by clicking the "Provide Feedback" tab at the right side of the page.

3

LIFE.wrx Browse

http://life.ccs.miami.edu/life/browse

4

LIFE.wrx Structure Search

http://life.ccs.miami.edu/life/structure

Draw a Structure and Search.

5

Life help

http://life.ccs.miami.edu/life/help

The LIFE search engine. Integrates all LINCS content leveraging a semantic knowledge model and common LINCS metadata standards. LIFE makes LINCS content discoverable and includes aggregate results linked to the Harvard Medical School. And other LINCS centers, who provide more information including experimental conditions and raw data. How do you search LIFE? LIFEwrx can be search by free text, using visualizations like the sunburst and hierarchical browsing and by drawing a chemical structure.

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LINKS TO THIS WEBSITE

lincs.hms.harvard.edu lincs.hms.harvard.edu

Reagents - HMS LINCS Project

http://lincs.hms.harvard.edu/resources/reagents

Library of Integrated Network-based Cellular Signatures. Please note that we are not in a position to supply cell lines, small molecules or protein reagents to external investigators. However, in the HMS LINCS Database. We provide information about the vendors from whom these reagents can be acquired. Additional cell types are regularly added to our collection as a result of collaboration with outside laboratories. Example cell types studied at HMS LINCS:. Breast cancer cells in the ICBP43 panel. Commerc...

lincsproject.org lincsproject.org

Tools & Databases - NIH LINCS Program

http://www.lincsproject.org/data/tools-and-databases

Library of Integrated Network-Based Cellular Signatures. Data and Signature Generation Centers. BD2K-LINCS Data Coordination and Integration Center. Pilot Phase 1 Centers. Data Production and Analysis (U54). Tools & Databases. Tools & Databases. BD2K-LINCS Data Coordination and Integration Center. Enrichr is an easy to use intuitive enrichment analysis web-based tool providing various types of visualization summaries of collective functions of gene lists. PMID: 23586463. SEP-L1000 (side effect prediction...

chembl.github.io chembl.github.io

ChEMBL blog

http://chembl.github.io/page2

Our projects on Github. As many of you know, SureChEMBL. Is one of our most recent resources, which taps into the wealth of knowledge hidden in the patent documents. More specifically, SureChEMBL extracts and indexes chemistry from the full-text patent corpus (EPO, WIPO and USPTO) by means of automated text- and image-mining, tirelessly, on a daily basis. If you would like learn more about SureChEMBL, its applications and exciting recent developments and future plans, we'll be giving a free. There you wi...

lincsproject.org lincsproject.org

Publications - NIH LINCS Program

http://www.lincsproject.org/publications

Library of Integrated Network-Based Cellular Signatures. Data and Signature Generation Centers. BD2K-LINCS Data Coordination and Integration Center. Pilot Phase 1 Centers. Data Production and Analysis (U54). Tools & Databases. Milani P, Escalante-Chong R, Shelley BC, Patel-Murray NL, Xin X, Adam M, Mandefro B, Sareen D, Svendsen CN, Fraenkel E (2016). Cell freezing protocol suitable for ATAC-Seq on motor neurons derived from human induced pluripotent stem cells. Nucleic Acids Research pii: gkw377. Sokolo...

lincs.hms.harvard.edu lincs.hms.harvard.edu

Data - HMS LINCS Project

http://lincs.hms.harvard.edu/data

Library of Integrated Network-based Cellular Signatures. All HMS LINCS data are available by browsing or searching the HMS LINCS Database. And many datasets can be visualized through customized graphical browsers accessible through our publication and project summary pages. For machine-driven data access. Interested users can learn more about our overall approach to data collection and presentation. By exploring this website and the publications. Arising from our Center. Reagents: Perturbagens and Cells.

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life.ccs.miami.edu life.ccs.miami.edu

LIFE - LINCS Information FramEwork

Browse by Small molecules(9072). Browse by Kinase proteins(475). The LIFE search engine integrates all LINCS content leveraging a semantic knowledge model and common LINCS metadata standards. LIFE makes LINCS content discoverable and includes aggregate results linked to the Harvard Medical School. And other LINCS centers, who provide more information including experimental conditions and raw data.

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