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Natural Products LINCHPIN Laboratory - Texas A&M Unviersity - College Station, TX

Natural Products LINCHPIN Laboratory. Emistry, and Natural P. About the LINCHPIN Lab. Welcome to the new co-Director, Dr. Ken Hull (formerly at AstraZeneca) who joined early April 2013 and brings fantastic drug discovery experience to the LINCHPIN Lab. The LINCHPIN Lab was recently awarded a CPRIT High Risk/High Impact Grant with the Plunkett group at MD Anderson to study the protein synthesis inhibitor, DMDAPatA, for chronic lymphocytic leukemia. (started May 2014) US Patent 7,230,021.

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Natural Products LINCHPIN Laboratory - Texas A&M Unviersity - College Station, TX | linchpin.tamu.edu Reviews
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Natural Products LINCHPIN Laboratory. Emistry, and Natural P. About the LINCHPIN Lab. Welcome to the new co-Director, Dr. Ken Hull (formerly at AstraZeneca) who joined early April 2013 and brings fantastic drug discovery experience to the LINCHPIN Lab. The LINCHPIN Lab was recently awarded a CPRIT High Risk/High Impact Grant with the Plunkett group at MD Anderson to study the protein synthesis inhibitor, DMDAPatA, for chronic lymphocytic leukemia. (started May 2014) US Patent 7,230,021.
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Natural Products LINCHPIN Laboratory - Texas A&M Unviersity - College Station, TX | linchpin.tamu.edu Reviews

https://linchpin.tamu.edu

Natural Products LINCHPIN Laboratory. Emistry, and Natural P. About the LINCHPIN Lab. Welcome to the new co-Director, Dr. Ken Hull (formerly at AstraZeneca) who joined early April 2013 and brings fantastic drug discovery experience to the LINCHPIN Lab. The LINCHPIN Lab was recently awarded a CPRIT High Risk/High Impact Grant with the Plunkett group at MD Anderson to study the protein synthesis inhibitor, DMDAPatA, for chronic lymphocytic leukemia. (started May 2014) US Patent 7,230,021.

INTERNAL PAGES

linchpin.tamu.edu linchpin.tamu.edu
1

Current Grants

http://linchpin.tamu.edu/currentgrants.php

Ldquo;Creating Novel Translation Inhibitors to Target Pro-survival Oncoproteins" Cancer Prevention and Research Institute of Texas, RP130660, PI: Daniel Romo Co-PI: William K. Plunkett, Jan. 2013-Nov. 2014. Ldquo;Mode of Action of the Amaryllidaceae Alkaloid Lycorine-Promising Anticancer Agent" National Institutes of Health (NCR), R15CA186046, PI: Alexander Kornienko Co-PI: Daniel Romo and Ken Hull, July 2014-June 2017.

2

Job Openings

http://linchpin.tamu.edu/jobopenings.php

Natural Products LINCHPIN Laboratory. Emistry, and Natural P. We are often looking for additional Post-Doctoral and Research Associates able to perform either (1) organic synthesis or (2) natural product isolation and structure elucidation. Please contact the co-Director, Dr. Ken Hull (ken.hull@chem.tamu.edu) for possible openings and further information. Diams; Web Accessibility. Diams; Site Policies.

3

About the LINCHPIN Lab

http://linchpin.tamu.edu/whatislinchpin.php

Natural Products LINCHPIN Laboratory. Emistry, and Natural P. About the LINCHPIN Lab. Capabilities and Available Instrumentation. The LINCHPIN thus brings together diverse researchers with common interests in bioactive natural products and derivatives along with associated proteomics tools (mainly mass spectral analysis both in the LINCHPIN Lab and also through the TAMU Laboratory for Biological Mass Spectrometry. Diams; Web Accessibility. Diams; Site Policies.

4

Publications and Patents

http://linchpin.tamu.edu/publications.php

Natural Products LINCHPIN Laboratory. Emistry, and Natural P. Natural Products LINCHPIN Laboratory Publications and Patents To Date. Ldquo;Role of an Active Site Loop in the Promiscuous Activities of Amycolatopsis sp. T-1-60 NSAR/OSBS" Andrew W. McMillan, Mariana S. Lopez, Minzhao Zhu, Benjamin C. Morse, In-cheol Yeo, Jaleesia Amos, Ken Hull, Daniel Romo, Margaret E. Glasner Biochemistry. Ldquo;Cre-activated translating ribosome affinity purification: a general tool for interrogation of translating RNAs ...

5

Staff Scientists

http://linchpin.tamu.edu/members.php

Natural Products LINCHPIN Laboratory. Emistry, and Natural P. Professor of Chemistry (2002-present). Director, Natural Products LINCHPIN Laboratory (2010-present). Director of Chemistry, TAMU Undergraduate MiniPharma (2010-present). Education: B.A., Chemistry/Biology, Texas A&M University. Ph D, Chemistry, Colorado State University (w/ Prof. Albert I. Meyers). Amer Cancer Soc. Post-Doctoral Fellow, Harvard University (w/ Prof. Stuart L. Schreiber). Dr Kenneth G. Hull. BS, Chemistry, University of Georgia.

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Natural Products LINCHPIN Laboratory. Emistry, and Natural P. About the LINCHPIN Lab. Welcome to the new co-Director, Dr. Ken Hull (formerly at AstraZeneca) who joined early April 2013 and brings fantastic drug discovery experience to the LINCHPIN Lab. The LINCHPIN Lab was recently awarded a CPRIT High Risk/High Impact Grant with the Plunkett group at MD Anderson to study the protein synthesis inhibitor, DMDAPatA, for chronic lymphocytic leukemia. (started May 2014) US Patent 7,230,021.

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