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Academia | The Offset
http://offset.peczuh.uconn.edu/tag/academia
Posts Tagged ‘Academia’. The Ride of a Lifetime: a Fulbright Experience. Posted by Mark W. Peczuh. Note: This is the long-read version of a post that appeared in the UConn Today. More photos from Barca on flickr. Research Collaboration: Let’s get the proteins to do the work. Life Outside the Lab: Diversions. The Heart of the Matter. In the spirit of the Fulbright program, I arranged interviews with a few scientists in Barcelona whose research interests are similar to mine. Interviews were extracurric...
offset.peczuh.uconn.edu
A Key to the Heart of Macrocyclic Structures | The Offset
http://offset.peczuh.uconn.edu/2013/10/07/a-key-to-the-heart-of-macrocyclic-structures
A Key to the Heart of Macrocyclic Structures. Positioning and Configuration of Key Atoms Influence the Topology of [13]-Macrodiolides. Jun Ma, Mark W. Peczuh* J. Org. Chem., 2013, 78, 7414 7422, DOI: 10.1021/jo400383g. October 7, 2013. Deconstructing a JACS communication: Winkler’s Ingenol synthesis. How to Organize your Orgo Lecture Notebook. A Chocolate Bloom Analogy for Crumbling Concrete in Home Foundations*. How VanA Strains Get Away With It, Part Two.
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Resistance: How VanA Strains Get Away With It | The Offset
http://offset.peczuh.uconn.edu/2015/08/23/resistance-how-vana-strains-get-away-with-it
Resistance: How VanA Strains Get Away With It. An evaluation of the thermodynamics of binding between various ligands of Vancomycin (Part 1/2). This post is also published on The Winnower. Under DOI: 10.15200/winn.144060.03577. In an effort to determine the relative importance of these effects, McComas. Figure 1. Vancomycin, VC. Figure by permission from Nature 1999, 397, 567-568. Vancomycin and VanA Resistance: A Primer. And the performance of the antibiotic against the ‘superbug’ methicillin-resistant.
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Brian Dunnigan | The Offset
http://offset.peczuh.uconn.edu/author/bcd04001
Author Archives: Brian Dunnigan. A Key to the Heart of Macrocyclic Structures. Positioning and Configuration of Key Atoms Influence the Topology of [13]-Macrodiolides. Jun Ma, Mark W. Peczuh* J. Org. Chem., 2013, 78, 7414 7422, DOI: 10.1021/jo400383g. October 7, 2013. How to Organize your Orgo Lecture Notebook. A Chocolate Bloom Analogy for Crumbling Concrete in Home Foundations*. How VanA Strains Get Away With It, Part Two.
offset.peczuh.uconn.edu
Deconstructing a JACS communication: Winkler’s Ingenol synthesis | The Offset
http://offset.peczuh.uconn.edu/2013/10/10/deconstructing-a-jacs-communication-winklers-ingenol-synthesis
Deconstructing a JACS communication: Winkler’s Ingenol synthesis. The First Total Synthesis of -Ingenol. Jeffrey D. Winkler,* Meagan B. Rouse, Michael F. Greaney,Sean J. Harrison, and Yoon T. Jeon. J Am Chem. Soc. Note: Many, many thanks go to Jeff Winkler. For looking over the post and also sharing an original copy of the manuscript. Which was itself spurred by Carmen Drahl’s reporting. A milestone in the synthesis. So it is up to the reader to work it out. Inspection of the structures shows that, ...
offset.peczuh.uconn.edu
Friendly Conversation | The Offset
http://offset.peczuh.uconn.edu/2015/08/24/friendly-conversation
So when the opportunity for some friendly conversation presents itself, I often go for it. (The antipode of friendly conversation. Conversation causes me physical pain, however.) As I read a research paper written by a student in my Physical Organic Chemistry class last semester (Spring 2015) I realized that turning it into a blog post would enable us to meet and discuss the topic and his treatment of it. J Am Chem. Soc. The post, Resistance: How VanA strains get away with it. Flowed out of Matt’s resear...
sciencegeist.net
Guest Writer: Mark Peczuh | ScienceGeist
http://sciencegeist.net/guest-writer-mark-peczuh
The spirit of science. Much ado about CO. Alchemy vs Chemistry: Same as it ever was. Interview with Xavier Salvatella – by Mark Peczuh →. Guest Writer: Mark Peczuh. June 5, 2013. Over the next several weeks, I am going to be hosting posts written by Mark Peczuh. Mark Peczuh (Photo Credit: UConn Chemistry. Mark is currently on a Fulbright Fellowship in Barcelona. He is working with Toni Planas. Of the Institute of Chemistry of Sarria. And I know you’ll all enjoy it! This entry was posted in Uncategorized.
offset.peczuh.uconn.edu
Etc. | The Offset
http://offset.peczuh.uconn.edu/tag/etc
Posts Tagged ‘Etc.’. The Ride of a Lifetime: a Fulbright Experience. Posted by Mark W. Peczuh. Note: This is the long-read version of a post that appeared in the UConn Today. More photos from Barca on flickr. Research Collaboration: Let’s get the proteins to do the work. Life Outside the Lab: Diversions. Once they arrived in Barcelona, my family and I roamed around Catalunya as unapologetic tourists. We visited the Gothic quarter, the Magic Fountain on Montjuic and all the Gaudí spots like Parc Guell.
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Natural Products | The Offset
http://offset.peczuh.uconn.edu/tag/natural-products
Posts Tagged ‘Natural Products’. Sympathy for the amide bond. Enantioselective Total Synthesis of (-)-Lansai B and -Nocardioazines A and B. Haoxuan Wang and Sarah E. Reisman. Angew Chem. Int. Ed. 6206-6210 DOI: 10.1002/anie.201402571. Nothing incites apoplexy in your favorite peptide chemist like mentioning how real synthetic chemists are dismissive of the challenges that can arise, from time to time, in the formation of amide bonds. C’mon. How hard can it really be? The strategy and execution of the wr...
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Summer Reads 2015 - Total Synthesis Communications | The Offset
http://offset.peczuh.uconn.edu/2015/07/01/summer-reads-2015-total-synthesis-communications
Summer Reads 2015 – Total Synthesis Communications. I assembled a list of journal articles reporting total syntheses of natural products based on suggestions from several people on Twitter. In addition to their subject matter, they are considered to be eloquently written. Read them to see if you agree or even make your own suggestion. The post is actually on Storify at the following URL:. July 1, 2015. Laquo; Sympathy for the amide bond. Resistance: How VanA Strains Get Away With It.
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