norcomm2.org
NorCOMM
http://www.norcomm2.org/index.php
NorCOMM2LS - Cre Drivers. The mouse is playing a pivotal role in understanding mammalian gene function. With its similar genome sequence, development, and physiology, the mouse is one of the preeminent model systems for the study of human development, normal biology, and disease. As part of the international effort to determine the function of every gene in the mammalian genome, The Centre for Phenogenomics. At The Hospital for Sick Children. And Mount Sinai Hospital's. Samuel Lunenfeld Research Institute.
norcomm2.org
DTCC
http://www.norcomm2.org/dtcc.php
Return to previous page. The Knockout Mouse Phenotyping Program (KOMP2). Is producing and phenotyping 2,500 knockout mouse lines from gene targeted ES cells generated by the first phase of the Knockout Mouse Project (KOMP). Three consortia are collaborating to make this happen. The Centre for Phenogenomics (TCP). Brings its expertise to one of these consortia, the DTCC. TCP is providing expertise and resources to several areas of activity within the DTCC:. Most of the baseline adult phenotyping for the D...
norcomm2.org
NorCOMM2 - Phenotyping - Project
http://www.norcomm2.org/norcomm2/index.php
Get the data you need for grant proposals, or explore gene function for gene candidates for disease, development, or drug target validation here. Genes passing ES cell QC. Genes in cohort production. NorCOMM2 contributes to an International Mouse Phenotyping Consortium. That will functionally annotate all 20,000 genes of the mammalian genome in the next 10 years (more info). NorCOMM2 will generate and phenotype 150 new knock-out mouse lines at TCP. Are nominated by Canadian scientists. L About Nor COMM.
norcomm2.org
NorCOMM2LS - Cre Drivers - Project
http://www.norcomm2.org/norcomm2LS/index.php
Spatial and temporal control of gene activity enables scientists to ask and answer questions about genes that function in multiple tissues and across different developmental stages. L About Nor COMM. This work was funded by the Government of Canada through. And the Ontario Genomics Institute.
mouseimaging.ca
Where is Autism Located in the Brain?
http://www.mouseimaging.ca/projects/embryonic_lethals.html
TCP Research and Support -. TCP Research and Facility Operations. THE TORONTO CENTRE FOR PHENOGENOMICS. The International Mouse Knockout Consortium (IMKC) is generating one mouse line with each of the known 23,000 genes in the mouse genome knocked out. It is known that about 30% of these will be embryonic lethal. However, it is still important to know what has failed and what has been the functional deficit associated with each knockout. 1 1 Wong MD, Dorr AE, Walls JR, Lerch JP, Henkelman RM (2012). ...
cmhd.ca
CMHD - ENU Mutagenesis & Physiology
http://www.cmhd.ca/enu_mutagenesis/index.html
TCP Research and Support -. TCP Research and Facility Operations. THE TORONTO CENTRE FOR PHENOGENOMICS. CENTRE FOR MODELING HUMAN DISEASE. TCP News and Events. Mutagenesis and Physiology Overview. Search Mutants by Phenotype. Search Mutants by Heritability. Physiology Assays and Protocols. View our full list of databases. 2004 Toronto Centre for Phenogenomics.
cmhd.ca
CMHD - Gene Trap
http://www.cmhd.ca/genetrap/index.html
TCP Research and Support -. TCP Research and Facility Operations. THE TORONTO CENTRE FOR PHENOGENOMICS. CENTRE FOR MODELING HUMAN DISEASE. TCP News and Events. Welcome to the Centre for Modeling Human Disease (CMHD) Gene Trap Resource – the PolyA Trap Resource of the International Gene Trap Consortium (IGTC). In which researchers are able to submit search criteria. Researchers will receive automated e-mail notification of matching gene trap clones as they are entered into the library and database. Canada...
cmhd.ca
CMHD - Gene Trap - Personnel
http://www.cmhd.ca/genetrap/personnel.html
TCP Research and Support -. TCP Research and Facility Operations. THE TORONTO CENTRE FOR PHENOGENOMICS. CENTRE FOR MODELING HUMAN DISEASE. TCP News and Events. CMHD Gene Trap Facility Members. William L. Stanford, Ph.D. – Director. Audrey I. Shukalyuk, Ph.D. – Postdoctoral Fellow. Laury Nutter, Ph.D. – NorCOMM Project Manager. Christine To, M.Sc. Programmer. Tammy Reid, M.Sc. – Head Technician. Qing Lan, M.D. – Tissue Culture Technician. Helen Zheng, M.Sc. – Molecular Biology Technician.
cmhd.mshri.on.ca
CMHD - Search Mutants by Phenotype
http://cmhd.mshri.on.ca/enu_mutagenesis/mice_reports/mice_reports_phenotype.asp
TCP Research and Support -. TCP Research and Facility Operations. THE TORONTO CENTRE FOR PHENOGENOMICS. CENTRE FOR MODELING HUMAN DISEASE. TCP News and Events. Search Mutants By Phenotype:. Muscular, Neurological and Behavior. Hematology and Blood Smear. Bone Density and Tissue Composition. 2004 Toronto Centre for Phenogenomics.
cmhd.mshri.on.ca
CMHD - Gene Trap - Primer
http://cmhd.mshri.on.ca/genetrap/primer.htm
TCP Research and Support -. TCP Research and Facility Operations. THE TORONTO CENTRE FOR PHENOGENOMICS. CENTRE FOR MODELING HUMAN DISEASE. TCP News and Events. The gene trap vector is introduced into ES cells by electroporation or retroviral infection and clones containing gene trap insertions are selected by antibiotic resistance. Antibiotic resistant clones are then picked into 96-well master plates, which are later replicated to generate frozen stocks for long-term storage of clones, cell lysates ...
