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ZF-HEALTH

Zebrafish Regulomics for Human Health

http://www.zf-health.org/

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CONTACTS AT ZF-HEALTH.ORG

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Max-Planck-Institut fuer Entwicklung

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ZF-HEALTH | zf-health.org Reviews
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Zebrafish Regulomics for Human Health
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2 zebrafish
3 genetics
4 sixth framework
5 mutants
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ZF-HEALTH | zf-health.org Reviews

https://zf-health.org

Zebrafish Regulomics for Human Health

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zf-health.org zf-health.org
1

ZF-HEALTH

http://www.zf-health.org/workpackages/wp3.html

Work Package 3: Characterisation of enhancer elements of human disease genes. We will perform a systematic characterisation of enhancer elements of potential disease genes. This characterisation will build on the concept of genomic regulatory blocks (GRBs) which contain highly conserved non-coding elements (HCNEs) acting as long-range enhancers of developmental genes (recently discovered by T. Becker in the ZF-MODELS. Project). We will:. Eventually we aim to extend our bioinformatic analysis to the entir...

2

ZF-HEALTH

http://www.zf-health.org/workpackages/wp4.html

Work Package 4: Gene expression mapping in the brain. We will provide knowledge and resources to facilitate rigorous assessment and understanding of normal brain development and neuronal differentiation as well as phenotypes affecting nervous system formation, function and viability. This will be achieved at two levels:. And have established suitable microscopy facilities and image analysis tools. Work Package Leader: UCL). Developed in the ZF-MODELS project) and through other databases.

3

ZF-HEALTH

http://www.zf-health.org/workpackages/wp2.html

Work Package 2: Phenotyping. We will conduct phenotyping in a three-tiered approach in order to create a comprehensive and data-rich annotation of the mutants and utilise the specialist expertise of the European zebrafish research community:. Initial phenotyping for morphology and behaviour at day 5 will be carried out by the laboratories that generate the mutants (mainly by GRL, UK). Work Package Leader: CNRS). Software and the PATO. Ontology. Within 6 months of the phenotyping they will submitted t...

4

ZF-HEALTH

http://www.zf-health.org/information/links.html

Other Framework projects on model organisms. FishForPharma is a Marie Curie Initial Training Network funded by the 7th Framework People Programme of the European Commission. The project will run for 4 years from January 2012. It brings together leading European research groups that have pioneered the use of zebrafish infection models and partners from the Biotech and Pharma sectors that aim to commercialise zebrafish tools for biomedical applications. The Zebrafish Information Network. These pages bring ...

5

ZF-MODELS

http://www.zf-health.org/zf-models

ZF-MODELS - Zebrafish Models for Human Development and Disease is an Integrated Project funded by the European Commission as part of its Sixth Framework Programme. EC Contract LSHG-CT-2003-503496). The project started on January 1, 2004 and is scheduled to run over a period of five years. The research effort is divided in five workpackages covering:. Analysis of expression patterns. Expression profiling and proteomics. For a more detailed summary, please download our flyer.

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bio1.uni-freiburg.de bio1.uni-freiburg.de

Driever Lab — Institut für Biologie I (Zoologie)

http://bio1.uni-freiburg.de/ebio-en/driever-lab-en

Only in current section. Animal Physiology / Neurobiology. DF Reiff selected Publications. MSc Biologie - Focus Genetics and Development. M Sc Biology- Focus Neurosciences. BSc and M.Sc. Molekulare Medizin. Evolutionary Biology and Animal Ecology. J Korb - Research. J Korb - Publications. J Korb - CV. Biology I - internal. Animal Physiology / Neurobiology. Evolutionary Biology and Animal Ecology. Biology I - internal. Institut für Biologie I (Zoologie). Prof Dr. Wolfgang Driever.

fishforpharma.com fishforpharma.com

Why zebrafish? - FishForPharma

http://www.fishforpharma.com/why-zebrafish-17

Zebrafish as model for studying human diseases. Zebrafish as a model for tuberculosis research. Tuberculosis is a dangerous threat to mankind. One third of the world population is carrier of a latent infection with. Strains have already appeared that are resistant against all known antibiotics. The hallmark of tuberculosis, in both zebrafish and human, is the long-term survival of mycobacteria in clusters of infected immune cells, the so-called granulomas. The human pathogen. Which is closely related to.

zfbiolabs.com zfbiolabs.com

Partners and Projects | ZF BioLabs

http://zfbiolabs.com/partners-and-projects

Within the research project ZF-Health (Zebrafish Regulomics for Human Health), ZF BioLabs has generated two morphant zebrafish for two rare diseases associated with. Mitochondrial enzymes, Friedreich’s ataxia. And has performed a moderate-throughput screening of compounds to identify suppressors of disease phenotypes. http:/ www.zf-health.org/. Collaborated as a partner in an European Research Project on laminophaties, using the Zebrafish as an animal model to study. ZF BioLabs developed the technology.

ezrc.kit.edu ezrc.kit.edu

KIT - European Zebrafish Resource Center (EZRC) - Homepage

http://www.ezrc.kit.edu/index.php

European Zebrafish Resource Center (EZRC). European Zebrafish Resource Center. Institute of Toxicology and Genetics. Tel: 49 721 608-22716. Welcome to the European Zebrafish Resource Center. We offer over 2,000 plasmids containing zebrafish genes, in conjunction with the Helmholtz Repository of Bioparts (HeRBi). Related Resources at KIT. European Society for Zebrafish Models in Biology and Medicine. ZFIN funding major concern. Our collaborators at the ZFIN model organism database need your help. Submit y...

zebrafishbrain.org zebrafishbrain.org

Zebrafish Atlas - Tutorial Example

http://www.zebrafishbrain.org/funding.php

There is significant overlap with other projects in the Wilson and Clarke labs. Both laboratories are part of the large scale consortium ZF-HEALTH which is part of the EU seventh framework partnership programme. The Wilson lab (UCL) is leader for work package 4: gene expression mapping in the brain. We will use zebrafishbrain.org to present information related to ZF-HEALTH tasks. Both Wilson (UCL) and Clarke labs (KCL) are also involved in work package 2: phenotyping. Dopaminergic cells in the subpallium.

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ZF-HEALTH

ZF-HEALTH - Zebrafish Regulomics for Human Health is a Large-scale Integrating Project funded by the European Commission as part of its Seventh Framework Programme. EC Grant Agreement HEALTH-F4-2010-242048). The project started on July 1, 2010 and is scheduled to run over a period of five and a half years. The research effort is divided in five workpackages covering:. Generation and distribution of mutants for potential human disease genes. Characterisation of enhancer elements of human disease genes.

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